This issue of Veterinary Clinics of North America: Small Animal Practice, with Editor Dr. Joao S. Orvalho, focuses on Topics in Cardiology. Article topics include: Feline Aortic Thromboembolism: Prevention and Therapy; Atrial fibrillation: Current Therapy; Cardiorenal Syndrome: Diagnosis and Management; Asymptomatic Canine Degenerative Valve Disease: Current and Future Therapies; Feline Congestive Heart Failure: Current therapies; Right Ventricular Function: Imaging Techniques; Arrhythmogenic Right Ventricular Cardiomyopathy: An Update; Real-Time 3-D Echocardiography: From Diagnosis to Intervention; Gene Therapy: Applications in Veterinary Cardiology; Interventional Cardiology: An Update; Asymptomatic Hypertrophic Cardiomyopathy: Diagnosis and Therapy.