This issue of Child and Adolescent Psychiatric Clinics, guest edited by Drs. Ellen House and John Tyson, will cover key topics of importance surrounding Psychosis in Children and Adolescents. This issue is one of four selected each year by our series Consulting Editor, Dr. Harsh Trivedi. Topics discussed in this issue include but are not limited to: Prodrome, Autism, Trauma, Medical Etiologies, Mood/Anxiety, Childhood onset schizophrenia, Substance Induced, Genetics of childhood onset schizophrenia, Neurocognition in youth with psychosis, Psychopharmacologic approaches, Community Based interventions, Evidence-Based Therapies for psychosis, School based approach to yout