The Practice of Reproducible Research presents concrete examples of how researchers in the data-intensive sciences are working to improve the reproducibility of their research projects. Each of the thirty-one case studies in this volume describes the workflow that an author used to complete a real-world research project, highlighting how particular tools, ideas, and practices have been combined to support reproducibility. Authors emphasize the very practical how, rather than the why or what, of conducting reproducible research. Part 1 contains an accessible introduction to reproducible research, a basic reproducible research project template, and a synthesis of lessons learned from across the thirty-one case studies. Parts 2 and 3 focus on the case studies. The Practice of Reproducible Research is an invaluable resource for students and researchers who wish to better understand the practice of data-intensive sciences and learn how to make their own research more reproducible.