With the discovery of planets beyond our solar system 25 years ago, exoplanet research has expanded dramatically, with new state-of-the-art ground-based and space-based missions dedicated to their discovery and characterisation. With more than 3,500 exoplanets now known, the complexity of the discovery techniques, observations and physical characterisation have grown exponentially. This Handbook ties all these avenues of research together across a broad range of exoplanet science. Planet formation, exoplanet interiors and atmospheres, and habitability are discussed, providing in-depth coverage of our knowledge to date. Comprehensively updated from the first edition, it includes instrumental and observational developments, in-depth treatment of the new Kepler mission results and hot Jupiter atmospheric studies, and major updates on models of exoplanet formation. With extensive references to the research literature and appendices covering all individual exoplanet discoveries, it is a valuable reference to this exciting field for both incoming and established researchers.