In this issue of Nursing Clinics of North America, guest editors Melodee Harris, Ann Kolanowski, and Sherry Greenberg bring their considerable expertise to the topic of Nursing Leadership in Long-Term Care. Leadership in nursing and long-term care is crucial to inspire, influence, and motivate staff to provide high-quality care in an interprofessional manner. Leaders must not only identify areas for improvement but act and support team members toward common goals. In this issue, leading geriatric nursing scholars  provide an in-depth understanding of what is needed to ensure effective professional nursing leadership in long-term care communities and the policy changes necessary to support quality care. Contains 13 relevant, practice-oriented topics including COVID-19 infection in long-term care; hospice and palliative care in nursing home residents with dementia; social isolation in long-term care; intraprofessional practice and delivery of nursing care; and more.  Provides in-depth clinical reviews on nursing leadership in long-term care, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.