In this issue of Clinics in Laboratory Medicine, guest editor Dr. Marisa C. Neilsen brings her considerable expertise to the topic of Infectious Disease Diagnostics. Top experts discuss current guidelines for infectious diseases diagnostics and emerging technology in the field of clinical microbiology; cover the strengths and weaknesses of current testing strategies and how laboratory results are used to guide treatment and improve patient outcomes; and explore how laboratories can adapt to the dynamic endemicity of pathogens, increasing antimicrobial resistance, and pandemics. Contains 14 relevant, practice-oriented topics including artificial intelligence; herpes B virus testing and challenges; cryptococcus; increased frequency of pulmonary NTM in the COVID-19 pandemic; Lyme disease diagnostics; and more Provides in-depth clinical reviews on infectious disease diagnostics, offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews