Throughout its history, the American West symbolized a place of hope and new beginnings, where anything was possible, especially for men. However, the history written until the 1970s and 1980s excluded women. Sigrid Schönfelder illustrates how the American West served as a catalytic gold mine for many transformations for women. It draws on the life narratives of three healthcare providers whose devotion within the social reform movements of the long nineteenth century contributed significantly to shaping healthcare policies. Their stories show how women contributed to place-making in the West and served as role models for other women to enter the field of medicine.