In this issue of Gastrointestinal Endoscopy Clinics of North America, guest editor Dr. Patrick Pfau brings his considerable expertise to the topic of Gastrointestinal Bleeding. Top experts in the field cover a broad range of topics on the diagnosis and treatment of both upper and lower gastrointestinal bleeding with a concentration on endoscopic intervention. This issue discusses the preparation of the patient with a GI bleed even before endoscopy is performed, and provides extensive coverage of the latest data and technology for variceal and non-variceal upper GI tract bleeding, small bowel/occult, and lower GI and colonic bleeding. Contains 12 relevant, practice-oriented topics including endoscopic diagnosis, grading, and treatment of bleeding peptic ulcer disease; variceal and non-variceal upper gastrointestinal bleeding refractory to endoscopic management: indications and role of interventional radiology; diagnosis of occult and obscure gastrointestinal bleeding; endoscopic treatment of small bowel bleeding; endoscopic diagnosis and treatment of colonic diverticular bleeding; and more. Provides in-depth clinical reviews on gastrointestinal bleeding, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.