In this issue of Orthopedic Clinics, guest editors from the esteemed Campbell Clinic bring their considerable expertise to the topic of Ethics and Professionalism in Orthopedics. Articles encompass the principles and standards that guide orthopedic surgeons in delivering care that is not only effective and efficient, but also respectful, compassionate, and just. Contains 10 relevant, practice-oriented topics including comorbidities in total hip and knee arthroplasty patients: when is it okay to say no?; caring for the underserved population in orthopaedic trauma; ethics in pediatric decision making and application process; ethical considerations in selection of procedure location: hospital vs surgery center; and more. Provides in-depth clinical reviews on ethics and professionalism in orthopedics, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.