This issue of Surgical Oncology Clinics of North America, guest edited by Drs. Usman Ahmad and Sudish Murthy, is devoted to Emerging Therapies in Thoracic Malignancies. Drs. Ahmad and Murthy has assembled expert authors to review the following topics: Mediastinal Germ Cell Tumors: Updates in Diagnosis and Management; Multidisciplinary Evaluation and Management of Early Stage Esophageal Cancer; Evaluation of Risk for Thoracic Surgery; Mesothelioma: Updates in Staging and Management; Chest Wall Sarcoma: When and Who to Resect and How to Reconstruct; Management of Locally Advanced Esophageal Cancer; Locally Advanced Lung Cancer and Salvage Resections; Siewert III Adenocarcinoma: Still Searching for the Right Treatment Combination; Current Indications for Pulmonary Metastasectomy; Lung Cancer Screening; Thymic Malignancies: Updates in Treatment and Staging; Intra-operative Detection and Assessment of Lung Nodules; Targeted Therapies, Immunotherapy and T-Cell Therapy in Lung Cancer; and more!