In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Peter A. Lee and John S. Fuqua bring their considerable expertise to the topic of Precocious and Delayed Puberty Revisited. Top experts provide practical discussions of physical evidence of early or late pubertal development, offering a reasonable approach to patients presenting with these chief complaints. Contains 12 relevant, practice-oriented topics including normal puberty; isolated vaginal bleeding before the onset of puberty; diagnosis, treatment, and outcome of males with CPP; hormone therapy during infancy or early childhood: has the time come?; and more. Provides in-depth clinical reviews on precocious and delayed puberty, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.