Animated children's comedy about a supervillain who has a change of heart. Trying to outdo his rival Vector (voice of Jason Segel), who has stolen the Great Pyramid of Giza, Gru (Steve Carell) hatches a plan to steal the Moon with the help of his army of Minions. Everything is going according to plan until three orphan girls, Margo (Miranda Cosgrove), Agnes (Elsie Fisher) and Edith (Dana Gaier), enter his life and his priorities begin to change.