In this issue, guest editors bring their considerable expertise to this important topic. Contains 16 practice-oriented topics including the burden of the "simple ankle sprains?: a review of the epidemiology and long-term impact; anatomy of the ankle and subtalar joint ligaments: what don't we know about it?; can weightbearing CT be a game-changer in the assessment of ankle sprain and ankle instability?; the role of needle arthroscopy in the assessment and treatment of ankle sprains; multidirectional ankle instability: what is it?; and more.  Provides in-depth clinical reviews on complexities involving the ankle sprain, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.