Squidge Dibley and his Year 6 classmates at Craglands South Primary School are facing their biggest, grossest problem ever.

When a freak accident at the talent quest unleashes a lice infestation that incapacitates almost the whole school, 6PU's arch-nemesis Hector Hoovesly takes over. Squidge and Padman quickly discover that this was no accident - instead, it is step one in Hoovesley's dastardly plan to take over first Craglands Primary, and then everything.

Defeating the world's most vile teacher will take guts, brains, and burps so powerful they can create mini earthquakes. There's only one kid for the job: SQUIDGE DIBLEY!